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A pilot prospective cohort study assessing the clinical utility of MRI evaluation of graft steatosis prior to transplantation will be conducted. An MRI of the donor liver within the transport cooler will be obtained on its way to the operating room.
The images from MRI will be analyzed to obtain information of fat content in all eight segments of the liver. Demographic, intra-operative, and post-operative patient data will be collected for each imaged graft.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MRI of donor liver | Experimental | MRI evaluation of graft steatosis in donor liver prior to transplantation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI of donor liver prior to transplant | Other | MRI of the on ice donor liver within the transport cooler on its way to the operating room |
|
| Measure | Description | Time Frame |
|---|---|---|
| Percent Hepatic Steatosis of a Donor Liver Prior to Transplantation | Amount of fat measured in the donor liver prior to transplant surgery using MRI scan | Measured immediately prior to liver transplant |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of steatosis percentages provided by biopsy to MRI results | Baseline | |
| Length of hospitalization of transplant recipient | Days to hospital discharge, approximately 2 weeks | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Bret D Alvis, M.D. | Vanderbilt University Medical Center | Principal Investigator |
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| ID | Term |
|---|---|
| D005234 | Fatty Liver |
| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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| Mortality of liver transplant recipient at 1 year post transplantation |
| 1 year |