The purpose of this study is to evaluate the efficacy of three doses of Florence oral suspension on changes of eosinophilic infiltration in esophageal biopsies.

Inclusion Criteria:

• Signed consent;

• Participants aged 18 years or more;

• Participants diagnosed with eosinophilic esophagitis, defined as:

  1. Presence of symptoms of esophageal dysfunction intermittently or continuously during previous week to the screening visit;
  2. Eosinophilic esophageal inflammation with ≥ 15 eosinophils/high-power field, in the screening endoscopy;
  3. Exclusion of other causes of esophageal eosinophilia.

Exclusion Criteria:

• Any clinical and laboratory findings that, in the judgment of the investigator, may interfere with the safety of research participants;
• Participants with a stricture on endoscopy that prevents passage of the endoscope;
• History of alcohol abuse or drug use;
• Use of concomitant therapies for any reason that may affect the assessment;
• History of gastroesophageal surgery;
• History of the abnormal gastrointestinal disorder;
• Another disorder that causes esophageal eosinophilia;
• Pregnancy or risk of pregnancy and lactating patients;
• Participants with known allergy, contraindication or hypersensitivity to the components of the medicine used in the clinical trial;
• Participation in clinical trial in the year prior to this study.