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The purpose of this study is to compare two slightly different methods of transcranial magnetic stimulation (TMS) to treat Post Traumatic Stress Disorder (PTSD)
This is a randomized single-blind pilot study investigating the efficacy of high-frequency repetitive transcranial magnetic stimulation (rTMS) applied to the right dorsolateral prefrontal cortex at either 10 Hz or 20 Hz as compared to a treatment as usual group for the treatment of Post Traumatic Stress Disorder (PTSD) symptoms.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treatment as usual | No Intervention | Treatment as usual, wait list control group | |
| rTMS at 10Hz | Active Comparator | 10 Hz rTMS of the right dorsolateral prefrontal cortex |
|
| rTMS at 20Hz | Active Comparator | 20 Hz rTMS of the right dorsolateral prefrontal cortex |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 10 Hz rTMS of the right dorsolateral prefrontal cortex | Other | Ten sessions of 10 Hz rTMS of the right dorsolateral prefrontal cortex |
|
| Measure | Description | Time Frame |
|---|---|---|
| Clinician Administered PTSD Scale , CAPS | The CAPS is the gold-standard, semi-structured interview that corresponds to DSM-IV criteria for PTSD. | day 10 |
| Measure | Description | Time Frame |
|---|---|---|
| Posttraumatic Stress Disorder Checklist, PCL | The PCL consists of 17 items measured on a 5-point Likert scale ranging from "not at all" to "extremely | week 24 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Marc A Capobianco, MD, DFAPA | NMCSD | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NMCSD | San Diego | California | 92134 | United States |
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| 20 Hz rTMS of the right dorsolateral prefrontal cortex | Other | Ten sessions of 20 Hz rTMS of the right dorsolateral prefrontal cortex |
|
| ID | Term |
|---|---|
| D003130 | Combat Disorders |
| ID | Term |
|---|---|
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |
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