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This study will target patients who have received a histopathological diagnosis of prostate cancer and who are undergoing treatment in various forms, including active PSA surveillance, surgical treatment, radiotherapy, endocrine therapy, and chemotherapy. The study will survey information about the patient at time of diagnosis, clinical staging, details of initial treatment, status of disease progression, and prognosis at the end point of the study. The purpose of the study is to clarify distribution of staging, the actual status of treatment choices and treatment outcomes.
The A-CaP will collect information in a linkable anonymized format from all medical institutions in Asian countries participating in the study and will engage in data analysis. J-CaP which has previous experience of engaging in a similar study in 2010 wll be a sponsor for A-CaP study, the aggregated results of which have been reported. The registration period for this study will be three years followed by 7 years of follow-up study, and research will be implemented across a wider range of Asian countries, with new institutions participating for the purposes of this study. As this study will be an observational study the acquisition of data will be relatively simple, and as the content of the study will be almost identical to the study conducted by J-CaP in 2010, a system for research implementation is already established at J-CaP.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Prostate Cancer | About 20,000 patients who have received a histopathological diagnosis of prostate cancer from ten countries in Asia. |
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| Measure | Description | Time Frame |
|---|---|---|
| Patients background at time of diagnosis of prostate cancer, treatment progress and prognosis with the reason for progression and subsequent treatment methods | The following items are examined for primary outcome measure.
| three years |
| Measure | Description | Time Frame |
|---|---|---|
| Patient QOL measured by SF-36 during treatment by comparison with A-Cap data and data in the United States and Australia | The short form 36 (SF-36) is used for an evaluation indicator of patient QOL. SF-36 includes the following eight elements.
More detailed questions are prepared under the above each eight element, which a score is produced for a quantitative outcome of the patients QOL. |
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Inclusion Criteria:
Exclusion Criteria:
• Patients for whom information about the time of diagnosis, including histopathological diagnosis, cannot be acquired.
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Prostate cancer patients
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| Name | Affiliation | Role |
|---|---|---|
| Hideyuki Akaza, M.D., Ph.D. | J-CaP | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Tokyo | Tokyo | Meguro-ku | 153-8904 | Japan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25098707 | Background | Onozawa M, Hinotsu S, Tsukamoto T, Oya M, Ogawa O, Kitamura T, Suzuki K, Naito S, Namiki M, Nishimura K, Hirao Y, Akaza H. Recent trends in the initial therapy for newly diagnosed prostate cancer in Japan. Jpn J Clin Oncol. 2014 Oct;44(10):969-81. doi: 10.1093/jjco/hyu104. Epub 2014 Aug 6. | |
| 19667269 | Background |
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| ID | Term |
|---|---|
| D011471 | Prostatic Neoplasms |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| three years |
| Cooperberg MR, Hinotsu S, Namiki M, Ito K, Broering J, Carroll PR, Akaza H. Risk assessment among prostate cancer patients receiving primary androgen deprivation therapy. J Clin Oncol. 2009 Sep 10;27(26):4306-13. doi: 10.1200/JCO.2008.21.5228. Epub 2009 Aug 10. |
| D005832 |
| Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |