This study is a randomized controlled trial (RCT) comparing adjuvanted influenza vaccine (AV) to unadjuvanted inactivated influenza vaccine (IIV). Children in Hutterite colonies in Alberta and Saskatchewan will receive AV or IIV. The goal of this study is to determine whether the AV vaccine, can provide increased community-wide protection.

Group A: Receive Intervention

Inclusion Criteria:

-Healthy children aged 6 months to 72 months

Exclusion Criteria:

• Anaphylactic reaction to a previous dose of influenza vaccine or to any of its components
• Known Immunoglobulin E (IgE)-mediated hypersensitivity to eggs manifested as hives, swelling of the mouth and throat, difficulty in breathing, hypotension, or shock
• Guillain- Barré syndrome within eight weeks of a previous influenza vaccine
• Use of aspirin or salicylate- containing products within 30 days before enrollment

Group B:

Inclusion Criteria:

• household and extended family members of children in Group A
• extended family is defined as the household members of the grandparents of the children in Group A

Exclusion Criteria:

• there are no exclusion criteria for this category of participants

Group C:

Inclusion Criteria:

• other Hutterite community members that are not in Group A

Exclusion Criteria:

• there are no exclusion criteria for this category of participants