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Traumatic coagulopathy is frequent and is an independent risk factor of mortality. Its detection mainly relies upon classic biological test like the prothrombin time and the international normaliezd ratio (INR). These tests are not available at the bedside. Point of care (POC) device for INR measurement are now available like the Coaguchek, Roche, France. The aim of the present study is to test the correlation between the POC INR and the laboratory INR.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Coagucheck, Roche, France | Device | Capillary puncture for POC INR measurement |
| Measure | Description | Time Frame |
|---|---|---|
| Concordance between POC INR and laboratory INR using 3 classes: normal < 1.1, moderate : 1.1-1.5, severe: >1.5 | Admission |
| Measure | Description | Time Frame |
|---|---|---|
| Prediction of RBC transfusion | 24 hours post admission | |
| Prediction of FFP transfusion | 24 hours post admission | |
| In-hospital mortality assessed using patients' files |
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Inclusion Criteria:
Exclusion Criteria:
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Patients admited for a suspicion of severe trauma wirth active bleeding in a level I trauma center
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28637514 | Derived | Mistral T, Boue Y, Bosson JL, Manhes P, Greze J, Brun J, Albaladejo P, Payen JF, Bouzat P. Performance of point-of-care international normalized ratio measurement to diagnose trauma-induced coagulopathy. Scand J Trauma Resusc Emerg Med. 2017 Jun 21;25(1):59. doi: 10.1186/s13049-017-0404-y. |
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| ID | Term |
|---|---|
| D014947 | Wounds and Injuries |
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| up to Day 28 |
| Injury severity (ISS) | Day 1 |
| Organ failure measured with the SOFA score at Day 1 | Day 1 |