Anatomical and Structural Connectivity in Two Psychotic Phenotypes : Periodic Catatonia and Cataphasia

Anatomical and Structural Connectivity in Schizophrenias

The different subtypes of Schizophrenia might have a disordered connectivity as their final common pathways.

The investigators will use multimodal structural MRI to assess anatomical connectivity on the one side and its functional consequence on functional connectivity on the other side to assess two phenotypes of psychosis : periodic catatonia and cataphasia in comparison with control subjects.

The coherence between structural and functional anomalies will be especially studied.

Inclusion criteria (controls):

• Aged from 18-65 Y
• Right handed

Additional inclusion criteria for patients:

• Schizophrenia according to the DSM5
• Either periodic catatonia or cataphasia according to the WKL classification
• Under stable medication regimen (> 1M)

Exclusion criteria:

• Current substance abuse
• Contraindication to MRI
• Past records susceptible to affect brain integrity
• Severe, unstable medical condition
• Pregnancy
• Patients deprived of their rights