Metacognitive Therapy for Obsessive-Compulsive Disorder

A Non-Inferiority Trial of Metacognitive Therapy Versus Exposure and Response Prevention for Individuals With Obsessive-Compulsive Disorder

Cognitive behavior therapy is the most effective treatment of obsessive-compulsive disorder. However, the majority of treated patients remain symptomatic. The metacognitive therapy by Wells (1997) could achieve substantial gains in first pilot studies. The purpose of this study is to investigate this approach with a randomized controlled trial by comparing metacognitive therapy with exposure and response prevention for obsessive-compulsive disorder.

The purpose of this study is to investigate metacognitive therapy by Wells (1997) with a randomized controlled trial by comparing metacognitive therapy with exposure and response prevention for obsessive-compulsive disorder.

Inclusion Criteria:

• Primary diagnosis: obsessive-compulsive disorder
• German-speaking
• Agreeing to participate, verified by completion of informed consent
• Stable medication (at least 4 weeks)

Exclusion Criteria:

• Current or past diagnosis of substance dependence, psychosis, neurological conditions
• Mental retardation