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The investigators will evaluate sensitization to animal allergens and allergic symptom during contacting animal allergens in Korean veterinary researchers who attend their annual conference.
The investigators will compare sensitization to animal allergen and other clinical and occupational factors between subjects who suffer from allergic symptom during contacting animal and those who do not.
The investigators will visit annual conference of Korean veterinary researchers.
After informed consent, Korean veterinary researchers who attend their conference and agree to enrollment into this study will be asked to respond to questionnaires regarding their gender, age, underlying allergic diseases, family history of allergic diseases, occupation and it's duration, contact animal and contact duration. Subjects will also be requested to report allergic symptom, causal animal and situation of contact including veterinary service, animal experiment, pet ownership, and ingestion if subjects suffer from allergic symptom when subjects contact animal.
Then, subjects will also be asked to undergo skin prick test for animal allergens including chicken feather and ten mammal epithelia as well as cow's milk, and hen's egg, four fish flesh and seven animal meats.
subjects will be divided into two group, subjects who suffer from allergic symptom during contacting animal and those who do not. Between two groups, sensitization to animal allergens as well as other demographic and occupational factors including gender, age, underlying allergic diseases, family history of allergic diseases, occupation and it's duration, contact animal and contact duration will be compared.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Subjects with animal allergy | Subjects who suffer from allergic symptom during contact with animal |
| |
| Subjects without animal allergy | Subjects who do not suffer from allergic symptom during contact with animal |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Animal allergy + | Other | Allergic symptom occurs when subject contact animal |
|
| Measure | Description | Time Frame |
|---|---|---|
| Skin reactivity to animal allergen in skin prick test | Mean diameter of wheal for animal allergen in skin prick test | on the day of survey (day 1) |
| Measure | Description | Time Frame |
|---|---|---|
| Underlying allergic disease | Underlying allergic disease including allergic rhinitis, asthma, atopic dermatitis, urticaria, food and drug allergy | on the day of survey (day 1) |
| Family history of allergic disease |
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Inclusion Criteria:
Exclusion Criteria:
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Korean Veterinary Researcher
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| Name | Affiliation | Role |
|---|---|---|
| Sang Min Lee, MD, PhD | Gachon University Gil Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gachon University Gil Medical Center | Incheon | 405-760 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 7390647 | Background | Blair A, Hayes HM Jr. Cancer and other causes of death among U.S. veterinarians, 1966-1977. Int J Cancer. 1980 Feb 15;25(2):181-5. doi: 10.1002/ijc.2910250203. | |
| 8972059 | Background | Elbers AR, Blaauw PJ, de Vries M, van Gulick PJ, Smithuis OL, Gerrits RP, Tielen MJ. Veterinary practice and occupational health. An epidemiological study of several professional groups of Dutch veterinarians. I. General physical examination and prevalence of allergy, lung function disorders, and bronchial hyperreactivity. Vet Q. 1996 Dec;18(4):127-31. doi: 10.1080/01652176.1996.9694711. |
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Individual participant will be informed of results of questionnaires and skin prick test immediately after they complete questionnaires and skin prick test
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| ID | Term |
|---|---|
| D065631 | Rhinitis, Allergic |
| D001249 | Asthma |
| D003876 | Dermatitis, Atopic |
| D014581 | Urticaria |
| D006967 | Hypersensitivity |
| ID | Term |
|---|---|
| D012220 | Rhinitis |
| D009668 | Nose Diseases |
| D012140 | Respiratory Tract Diseases |
| D012130 | Respiratory Hypersensitivity |
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| Animal allergy - | Other | Allergic symptom does not occur when subject contact animal |
|
Family history of allergic disease including allergic rhinitis, asthma, atopic dermatitis, urticaria, food and drug allergy
| on the day of survey (day 1) |
| Occupation | Type of occupation including veterinary service and veterinary experiment | on the day of survey (day 1) |
| Duration of occupation | Duration of occupation (year) | on the day of survey (day 1) |
| Contact animal | Kinds of animals that subjects contact | on the day of survey (day 1) |
| Contact time | Duration of animal contact (hour/day) | on the day of survey (day 1) |
| Causal animal | Animal that provokes allergic symptom when subject contact it | on the day of survey (day 1) |
| Contact situation | Situation including veterinary service, veterinary research, ingestion and pet ownership in which subject contact animal that provokes allergic symptom | on the day of survey (day 1) |
| Allergic symptom during contacting animal | Allergic symptom including itchy eyes, nose and skin, rhinorrhea, sneezing, nasal congestion, postnasal drip, dyspnea, wheezing, cough, sputum, chest pain or discomfort, urticaria, rash, and angioedema when subject contact animal | on the day of survey (day 1) |
| 21632519 | Background | Samadi S, Spithoven J, Jamshidifard AR, Berends BR, Lipman L, Heederik DJ, Wouters IM. Allergy among veterinary medicine students in The Netherlands. Occup Environ Med. 2012 Jan;69(1):48-55. doi: 10.1136/oem.2010.064089. Epub 2011 May 31. |
| 24003386 | Background | Park YB, Mo EK, Lee JY, Kim JH, Kim CH, Hyun IG, Choi JH. Association between pet ownership and the sensitization to pet allergens in adults with various allergic diseases. Allergy Asthma Immunol Res. 2013 Sep;5(5):295-300. doi: 10.4168/aair.2013.5.5.295. Epub 2013 Jun 25. |
| 25104279 | Result | Moghtaderi M, Farjadian S, Abbaszadeh Hasiri M. Animal allergen sensitization in veterinarians and laboratory animal workers. Occup Med (Lond). 2014 Oct;64(7):516-20. doi: 10.1093/occmed/kqu097. Epub 2014 Aug 7. |
| 4025958 | Result | Lutsky I, Baum GL, Teichtahl H, Mazar A, Aizer F, Bar-Sela S. Occupational respiratory disease in veterinarians. Ann Allergy. 1985 Aug;55(2):153-6. |
| 12874849 | Result | Susitaival P, Kirk JH, Schenker MB. Atopic symptoms among California veterinarians. Am J Ind Med. 2003 Aug;44(2):166-71. doi: 10.1002/ajim.10253. |
| 17021840 | Result | Krakowiak A, Wiszniewska M, Krawczyk P, Szulc B, Wittczak T, Walusiak J, Palczynski C. Risk factors associated with airway allergic diseases from exposure to laboratory animal allergens among veterinarians. Int Arch Occup Environ Health. 2007 May;80(6):465-75. doi: 10.1007/s00420-006-0153-0. Epub 2006 Oct 5. |
| 3477686 | Result | Will LA, Nassif EG, Engen RL, Patterson RA, Zimmerman D. Allergy and pulmonary impairment in Iowa veterinarians. N Engl Reg Allergy Proc. 1987 May-Jun;8(3):173-7. doi: 10.2500/108854187778984645. |
| 23772565 | Result | Samadi S, Wouters IM, Heederik DJ. A review of bio-aerosol exposures and associated health effects in veterinary practice. Ann Agric Environ Med. 2013;20(2):206-21. |
| D010038 |
| Otorhinolaryngologic Diseases |
| D006969 | Hypersensitivity, Immediate |
| D007154 | Immune System Diseases |
| D001982 | Bronchial Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012873 | Skin Diseases, Genetic |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D003872 | Dermatitis |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D017443 | Skin Diseases, Eczematous |
| D017445 | Skin Diseases, Vascular |