Intestinal Fatty Acid Binding Protein in Very Low Birth Weight Infants With Meconium Obstruction

The Clinical Utility of Urine Intestinal Fatty Acid Binding Protein in the Management of Very Low Birth Weight Infants With Meconium Obstruction

Urinary intestinal fatty acid binding protein (i-FABP), a marker of intestinal mucosal cell damage, has recently been proposed as a clinically useful measure in the early detection of necrotizing enterocolitis (NEC). However, there are no data on urinary i-FABP in meconium obstruction of prematurity (MOP). This study aimed to evaluate urinary i-FABP in MOP patient as a marker for early detection.

Inclusion Criteria:

• preterm infants weighing <1,250g

Exclusion Criteria:

• major congenital anomalies
• perinatal asphyxia (cord pH <7.0)