Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease

Disease Progression and Clinical Outcomes in Chronic Hepatitis B (CHB) Patients With Comorbid Nonalcoholic Fatty Liver Disease (NAFLD)

The purpose of this study is to determine the disease progression in CHB/NAFLD compared with CHB and NAFLD including liver cirrhosis, cirrhotic complications and hepatocellular carcinoma (HCC).

Inclusion Criteria:

• Liver biopsy proved CHB and/or NAFLD at baseline;
• Chinese
• Follow-up duration>12 months

Exclusion Criteria:

• Other liver diseases;
• Secondary causes of hepatic steatosis;
• Alcohol abuse;
• Liver cirrhosis, cirrhosis related complications or HCC at baseline;
• Malignancy;
• History of liver transplantation