The loss of central vision causes difficulty not only in reading but also in faces recognition, and in particular in the identification of facial expression, objects or spaces. These visual deficits have been mainly studied in relation with reading, which is the main complaint of these kind of patients. However, there are not enough data regarding perception of objects and spaces in this population. Then, the objectives are to study the visual-spatial abilities in individuals with vision loss, and altered cognitive processes, (2) to develop clinics tools for early detection and quantification of visual-spatial deficits and (3)to understand the capacities of normal peripheral vision in order to test the possibility of potential training for use of peripheral vision when central vision is impaired by an ophthalmic pathology.

Inclusion Criteria cases:

• Patients with eye disease causing loss of central or peripheral vision
• French speakers
• Age between 18 and 90 years old
• Written consent
• Health insurance

Inclusion Criteria controls:

• Sex and age matched controls (+/- 5 years)
• French speakers
• Normal visual examination with visual acuity of min 9/10

Exclusion Criteria:

• Psychiatric disease or neurological pathologies
• Communication difficulties (deafness / mutism)
• Drug treatment altering concentration
• Mental deterioration with MMS <24
• Alcoholism or addiction to drugs
• Persons under guardianship

Patients with eye disease causing loss of central or peripheral vision