Locally Applied Pressure-induced Vasodilatation | NCT02861924 | Trialant

Locally Applied Pressure-induced Vasodilatation | NCT02861924 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
microcirculatory responses	Experimental	Measure microcirculatory responses after localized ischemia obtained by local application of pressure (laser speckle). A pressure is applied to the subject's arm. this causes a localized ischemia. the measures responses to this ischemia will be made by the imager speckle (LSCI) give the microvascular perfusion data.	Other: microcirculatory responses

Interventions

Name	Type	Description	Arm Group Labels	Other Names
microcirculatory responses	Other	The effect of the duration and intensity of the pressure; reproducibility and correlation with ischemic hyperemia post. measurements are made with the Imager SPECKLE imager (LSCI) give the microvascular perfusion data in arbitrary units called perfusion units (UP).

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
microcirculatory response to local pressure. Measurements are made with the Imager SPECKLE imager (LSCI) give the microvascular perfusion data in arbitrary units called perfusion units (UP).	Measurements are made with the Imager SPECKLE imager (LSCI) give the microvascular perfusion data in arbitrary units called perfusion units (UP).	2 hours

Contacts/Locations Module

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
30399363	Derived	Henni S, Hersant J, Loufrani L, Duval G, Humeau-Heurtier A; SIMS Group; Riou J, Abraham P; SOCOS Group. Painless local pressure application to test microvascular reactivity to ischemia. Microvasc Res. 2019 Mar;122:13-21. doi: 10.1016/j.mvr.2018.10.013. Epub 2018 Nov 3.