An Open-Label Study To Evaluate the Efficacy and Safety of Ocrelizumab in Patients With Relapsing Multiple Sclerosis Who Have A Suboptimal Response to an Adequate Course of Disease-Modifying Treatment
An Open-Label Study To Evaluate the Efficacy and Safety of Ocrelizumab in Patients With Relapsing Multiple Sclerosis Who Have A Suboptimal Response to an Adequate Course of Disease-Modifying Treatment
The purpose of this prospective, multicenter, open-label, efficacy, and safety study is to assess the efficacy and safety of ocrelizumab in participants with Relapsing Remitting Multiple Sclerosis (RRMS) who have had a suboptimal response to an adequate course of a Disease-Modifying Treatment (DMT). The study will consist of a Screening period (up to 4 weeks), an Open-label treatment period (96 weeks; with last dose administered at Week 72), and a Follow-up period of at least 2 years.
Inclusion Criteria:
Exclusion Criteria:
Bron, 69677, France
Clermont-Ferrand, 63003, France
Berg, 82335, Germany
Bonn, 53111, Germany
Dresden, 01307, Germany
Düsseldorf, 40211, Germany
Erbach/Odenwald, 64711, Germany
Freiburg im Breisgau, 79106, Germany
Hamburg, 20246, Germany
Hamburg, 22083, Germany
Hanover, 30171, Germany
Kassel, 34121, Germany
Magdeburg, 39120, Germany
München, 81675, Germany
Neuruppin, 16816, Germany
Oldenburg in Holstein, 23758, Germany
Westerstede, 26655, Germany
Chieti, Abruzzo 66013, Italy
L’Aquila, Abruzzo 67100, Italy
San Giovanni Rotondo, Apulia 71013, Italy
Naples, Campania 80131, Italy
Naples, Campania 80131, Italy
Bologna, Emilia-Romagna 40139, Italy
Rome, Lazio 00133, Italy
Rome, Lazio 00152, Italy
Rome, Lazio 00168, Italy
Bergamo, Lombardy 24127, Italy
Gallarate, Lombardy 21013, Italy
Milan, Lombardy 20122, Italy
Milan, Lombardy 20132, Italy
Milan, Lombardy 20133, Italy
Pavia, Lombardy 27100, Italy
Pozzilli, Molise 86077, Italy
Catania, Sicily 95123, Italy
Palermo, Sicily 90129, Italy
Palermo, Sicily 90146, Italy
Ancona, The Marches 60100, Italy
Florence, Tuscany 50134, Italy
Siena, Tuscany 53100, Italy
Perugia, Umbria 06156, Italy
Verona, Veneto 37134, Italy
Sittard-Geleen, 6162 BG, Netherlands
L'Hospitalet de Llobregat, Barcelona 08907, Spain
A Coruña, LA Coruña 15006, Spain
Lleida, Lerida 25198, Spain
Vigo, Pontevedra 36312, Spain
Oviedo, Principality of Asturias, Spain
Istanbul, 34098, Turkey (Türkiye)