Study has been terminated due to small sample size

A prospective, open-label, and multi-centered feasibility registry.

This is a prospective, open-label, and multi-centered feasibility registry (single arm study). Approximately 36 subjects with prohibitive risk degenerative mitral regurgitation (DMR) who receive at least 1 commercial MitraClip will be registered at up to 10 US sites.

Inclusion Criteria:

• Subject must consent to receiving the MitraClip device
• Subject must consent, be able, and commit to wearing the Actiwatch continuously for approximately 7 months
• Subject must consent to use of their data from this registry for purposes of exploratory research and publication and presentation

Exclusion Criteria:

• Subject is not a member of vulnerable population
• Subject must not have any disabilities that preclude reliable data collection from the Actiwatch, e.g., epilepsy with uncontrolled recurring episodes, serious stage degenerative/disabling disease (e.g. Parkinson's disease), inability to walk or will require walking aids, etc.

Prohibitive risk degenerative mitral regurgitation (DMR) patients who receive at least 1 commercial MitraClip