The purpose of this study is to determine the factors associated with acceptability to oral HIV pre-exposure prophylaxis (PrEP) among Thai men who have sex with men (MSM) and transgender women (TGW).

Inclusion Criteria:

• MSM or TGW at age18 years or older at enrollment
• Able to read and write effectively in Thai language
• Negative HIV testing (by assigned rapid tests) at enrollment
• Available to return for the study visits and willing to comply with study requirements
• Willing to provide reachable contact numbers and address
• Creatinine clearance ≥ 60 mL/min
• Negative urine protein
• Negative HBs Ag

Exclusion Criteria:

• Symptoms suggestive for acute HIV seroconversion
• Participating in any interventional HIV research
• Has any physical or mental condition(s) that, in the opinion of the investigator(s), complicate interpretation of study outcome data

Thai MSM and TGW