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A pilot study to assess the accuracy and acceptability of a magnet assisted capsule endoscopy in detecting esophageal pathology compared to standard endoscopy.
This will be a single centre feasibility study performed at Nottingham University Hospitals NHS Trusts.
We will assess the accuracy of MACE compared to gastroscopy in diagnosing Barretts oesophagus and esophageal varices. Patients will have both tests on the same ay, with the endoscopic findings compared.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MACE | Experimental | MACE procedure |
|
| OGD | Active Comparator | Clinically indicated gastroscopy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Magnet assissted capsule endoscopy | Device | Patients due to have a clinically indicated gastroscopy will be asked to have a MACE procedure on the same day |
|
| Measure | Description | Time Frame |
|---|---|---|
| Diagnostic accuarcy | endoscopic | immediate |
| Measure | Description | Time Frame |
|---|---|---|
| comfort | questionnaire | 2 weeks |
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Inclusion Criteria:
Due to have a clinically indicated gastroscopy Barrett's oesophagus/ oesophageal varices or Controls Able to give informed consent
Exclusion Criteria:
Unable to give consent Pregnant Pacemaker swallowing difficulties
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| Name | Affiliation | Role |
|---|---|---|
| Krish Ragunath | Nottingham University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nottingham University Hospital | Nottingham | NG7 2UH | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31678203 | Derived | Beg S, Card T, Warburton S, Rahman I, Wilkes E, White J, Ragunath K. Diagnosis of Barrett's esophagus and esophageal varices using a magnetically assisted capsule endoscopy system. Gastrointest Endosc. 2020 Apr;91(4):773-781.e1. doi: 10.1016/j.gie.2019.10.031. Epub 2019 Oct 31. |
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| ID | Term |
|---|---|
| D001471 | Barrett Esophagus |
| D004932 | Esophageal and Gastric Varices |
| ID | Term |
|---|---|
| D011230 | Precancerous Conditions |
| D009369 | Neoplasms |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
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| ID | Term |
|---|---|
| D004724 | Endoscopy |
| ID | Term |
|---|---|
| D003949 | Diagnostic Techniques, Surgical |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D019060 | Minimally Invasive Surgical Procedures |
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| D004066 |
| Digestive System Diseases |
| D006975 | Hypertension, Portal |
| D008107 | Liver Diseases |
| D013514 | Surgical Procedures, Operative |