The Effects of Focal Vibration on Spasticity in Multiple Sclerosis Patients

The Effects of Focal Vibration on Central and Peripheral Spasticity in Multiple Sclerosis Patients. A Randomized, Multicenter, Double Blinded vs Placebo Study

This trial consists of application of little devices (named Equistasi®) generating focal vibrations to treat spasticity in neurological patients, affected by multiple sclerosis. The expected effects are on gait and postural instability.

Inclusion Criteria:

• Multiple Sclerosis affected
• Spasticity
• EDSS (Expanded Disability Status Scale) 0 - 5,5
• Patients able to sign informed consent

Exclusion Criteria:

• Age less than 18 years old and more than 65 years old
• Pacemaker
• Pregnancy
• Comorbidities as: cancer, hypertension not controlled by drugs
• concurrent therapies with antidepressant or corticosteroids