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Surgical repair of perineal lesions after delivery can be associated with infection of the surgery site. The aim of this study was to compare the surgical site infection with triclosan-coated suture (Vicryl Plus) versus coated suture (Vicryl) in the episiotomy after delivery.
Women undergoing planned were randomized to either episiotomy suture with VICRYL PLUS or VICRYL. The primary outcome measures were number of sutures used and the development of hematoma, seroma, surgical site infection (SSI) or wound disruption one week after episiotomy. Secondary outcome measures were the cost of the treatment with or without infection, and scar evaluation (wound complication).
Data were analyzed according to the intention to treat principle.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| VICRYL PLUS | Active Comparator | triclosan-coated sutures |
|
| VICRYL | Active Comparator | non antibacterial coated sutures |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| vicryl plus suture | Procedure | episiotomy with triclosan-coated sutures |
| |
| Measure | Description | Time Frame |
|---|---|---|
| number of sutures used | two hours | |
| number of patients with wound complications (infection, hematoma, disruption) | one week |
| Measure | Description | Time Frame |
|---|---|---|
| cost of the treatment with and without infection | cost of the treatment with and without infection | two weeks |
| number of patients with adverse outcomes | two weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| AMIRA AYACHI, Ph D | Contact | 53660148 | 00216 | benmrad.amira@yahoo.fr |
| AMIRA AYACHI, Ph d | Contact |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Bougatfa | Recruiting | Bizerte | 7000 | Tunisia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26850191 | Result | Guo J, Pan LH, Li YX, Yang XD, Li LQ, Zhang CY, Zhong JH. Efficacy of triclosan-coated sutures for reducing risk of surgical site infection in adults: a meta-analysis of randomized clinical trials. J Surg Res. 2016 Mar;201(1):105-17. doi: 10.1016/j.jss.2015.10.015. Epub 2015 Oct 23. |
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| ID | Term |
|---|---|
| D007239 | Infections |
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| ID | Term |
|---|---|
| D011098 | Polyglactin 910 |
| D013537 | Sutures |
| ID | Term |
|---|---|
| D011091 | Polyesters |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
| D001697 | Biomedical and Dental Materials |
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| vicryl suture |
| Procedure |
episiotomy with non antibacterial coated suture |
|
| D008420 |
| Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |
| D053831 | Surgical Fixation Devices |
| D013523 | Surgical Equipment |
| D004864 | Equipment and Supplies |