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This present investigation aims to determine whether a transversus abdominous plane(TAP) block, utilizing liposomal bupivacaine (Exparel), at the conclusion of a cesarean section decreases post-operative pain. The hypothesis is that performance of the TAP block with liposomal bupivacaine will decrease post-operative narcotic use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo- Tap block w normal saline | Placebo Comparator | After completion of surgery with closer of skin incision a TAP block will be performed. On confirmation of entering the fascial plane, 20cc of Normal saline will be injected after negative aspiration. That will complete the intervention. 20 patients will be in this arm |
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| Intervention-Tap block w Liposomal bupivacaine | Experimental | After completion of surgery w closure of skin incision a TAP block will be performed. On confirmation of entering the fascial plane, Liposomal bupivacaine 0.33% (10 ml diluted to 20 ml using sterile normal saline) will be injected after negative aspiration. That will complete the intervention. 20 patients will be in this arm |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| TAP block w Liposomal bupivacaine | Drug | TAP block w Liposomal bupivacaine diluted to 0.66% (20 mLs) |
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| Measure | Description | Time Frame |
|---|---|---|
| Postoperative narcotic use | Patient use of standard postoperative narcotics (percocet) will be measured. | initial 48 hours postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Subjective pain scores using 1-10 VAS system | Subjective pain scores using 1-10 VAS system will be measured | initial 48 hours postoperatively |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jaimey Pauli, MD | Milton S. Hershey Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | United States |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| TAP block w normal saline | Procedure | TAP block w normal saline -preservative free 0.9% sodium chloride (20mLs) |
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