Validation of Noninvasive Hemoglobin, Comparison of PVI to Standard Methods, and Validation of Clinical Efficacy of ORI

Validation of a Pulse Oximetry Based Hemoglobin Measurement System. Comparison of Plethysmographic Variability Index to Standard Methods of Guiding Fluid and Transfusion Management in the Critically Ill Adult Patients. Validation of Clinical Efficacy of ORI for Supplemental Oxygen Titration

The study goal is to establish the correlation of hemoglobin values determined by the noninvasive pulse oximetry-determined hemoglobin (SpHb) system with hemoglobin as measured by other validated devices. The study will also evaluation oxygen reserve index (ORI) to correlate with partial pressure of oxygen (PaO2), and to evaluate pleth variability index (PVI) with stroke volume variation (SVV) or pulse pressure variation (PPV) values.

Inclusion Criteria:

• Admitted into the ICU
• Aged 18 years or older
• Mechanically ventilated
• Arterial line placed
• Vigileo/Flotrac System being used for guidance of fluid management

Exclusion Criteria:

• Pregnancy
• Prisoner status
• Extreme hemodynamic instability
• Multiple vasopressors in use with questionable peripheral blood flow
• Lack of appropriate sites for sensor placement
• Patient or patient's legal representative refusal