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The primary objective of this study is to describe mortality of newborns who received basic, advanced or no neonatal resuscitation immediately after birth at Shoklo Malaria Research Unit.
This is a retrospective, descriptive study of hospital records will be conducted. The existing dataset of newborns of ≥28 weeks gestation delivered at Shoklo Malaria Research Unit clinics from January 2008 to December 2015 will be analysed.
In the dataset, 15224 newborns fulfill the inclusion criteria and therefore they will all be analysed with IBM SPSS Statistics 22 for Windows.
Descriptive statistics will be used to define: a) the proportion of newborns alive at 24 hours, 7 days, 28 days, and at 1 year, following resuscitation at SMRU birthing rooms and b) the number of newborns requiring basic and advanced resuscitation.
Measurements of correlation coefficient will be used to compare Shoklo Developmental test scores and developmental milestones attained at 1 year in resuscitated and non-resuscitated infants. The Pearson correlation coefficient will be used if the relationship between two variables is found to be linear.
Antenatal, perinatal and postnatal characteristics associated with neonatal resuscitation will be defined by logistic regression analysis.
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| Measure | Description | Time Frame |
|---|---|---|
| Mortality 24 hours after birth of babies who received basic resuscitation | 24 hours | |
| Mortality 24 hours after birth of babies who received advanced resuscitation | 24 hours | |
| Mortality 24 hours after birth of babies who did not receive neonatal resuscitation | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality at 7 days | 7 days | |
| Mortality at 28 days | 28 days | |
| Mortality at one year |
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Inclusion Criteria:
Exclusion Criteria:
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All liveborn, singletons, ≥28 weeks gestation, birthed at SMRU, from 1 January 2008 to 31 December 2015 will be included.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shoklo Malaria Research Unit | Mae Sot | Changwat Tak | 63110 | Thailand |
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| 1 year |
| Proportion of live births requiring basic or advanced neonatal resuscitation. | 24 hours |
| Number of newborns who received basic resuscitation, as a proportion of all live births. | 24 hours |
| Number of newborns who received advance resuscitation, as a proportion of all live births. | 24 hours |
| Shoklo Developmental test scores at 1 year in infants who received basic or advanced neonatal resuscitation or no resuscitation. | up to 1 year of age |
| Month of achieved milestones (crawl, walk, talk) in in infants who received basic or advanced neonatal resuscitation or no resuscitation. | up to 1 year of age |
| characteristics of antenatal infant receiving neonatal resuscitation compared to non-resuscitated infants as assessed by physiological parameter | 24 hours |
| characteristics of perinatal infants receiving neonatal resuscitation compared to non-resuscitated infants as assessed by physiological parameter | 24 hours |
| characteristics of neonatal infants receiving neonatal resuscitation compared to non-resuscitated infants as assessed by physiological parameter | 24 hours |