Hydrosorb® Versus Control in the Management of Radio-induced Skin Toxicity: Multicentre Controlled Phase III Randomized Trial

Hydrosorb® Versus Control (Water Based Spray) in the Management of Radio-induced Skin Toxicity: Multicentre Controlled Phase III Randomized Trial

The primary objective consisted of avoiding deterioration and/or restoring the integrity of the skin of patients treated by radiotherapy, right from the first signs of grade 1 or 2 radiation dermatitis.

Inclusion Criteria:

• Women treated by normo fractionated radiotherapy for breast cancer
• Presenting grade 1 or 2 radiation dermatitis during the treatment and who provided their written informed consent were included in the study.

Exclusion criteria:

• Were male patients
• Radiation dermatitis already treated or caused by another treatment
• Subjects deprived of their freedom or under guardianship
• Subjects in whom medical follow-up was impossible
• A cancer wound or skin flap on the irradiated zone
• A history of allergic skin reaction
• Concomitant chemotherapy or concomitant bevacizumab therapy and bilateral irradiation.