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| Name | Class |
|---|---|
| Hospital Nacional de Parapléjicos de Toledo | OTHER |
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The purpose of this study is to determine whether the transcutaneous application of unmodulated high frequency alternating currents could produce a quickly conduction block of peripheral nerve.
In the last years several animal experimental studies have evidenced that high frequency unmodulated currents about 5 KHz can cause a peripheral nerve block. However electric currents with these high frequencies that are usually used for the treatment of pain in humans are interrupted or modulated (i.e. interferential currents).
It has show that the diameter of the nerve it is related with the frequency to produce the conduction block. For this reason we decided to applied 30KHz to observe the effects on pain in patients with whiplash and to compare versus sham stimulation.
Only one study has applied 5KHz on experimental pain and they have demonstrated changes in somatosensory thresholds.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High-Frequency | Experimental | Transcutaneous application of high frequency electrical current over the arm for a 30 minutes session. The intensity of the current will increase until participants report a "strong but comfortable" sensation, just below motor threshold. |
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| Sham Stimulation | Sham Comparator | Electrodes are placed over the arm for a 30 minutes in the same manner as experimental group but will be applied a sham electrical stimulation increasing the current intensity of an unconnected channel. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High-Frequency | Device | high-Frequency electrical stimulation over superficial radial nerve through the electrotherapy device Myomed 932. (Enraf-Nonius, Delft, Netherlands) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Baseline Mechanical Pain Threshold | The pressure pain threshold will be measured by a pressure algometer and will be expressed in Newton | baseline at 0 min |
| Baseline Tactile Threshold | The tactile threshold will be measured with Von Frey filaments and will be expressed in millinewton | baseline at 0 min |
| Baseline Muscle Strength | The muscle strength will be measured with a dynamometer and will be expressed in Newton | Baseline at 0 min |
| Mechanical Pain Threshold after treatment at 30 min | The pressure pain threshold will be measured by a pressure algometer and will be expressed in Newton | Immediately after treatment at 30 min |
| Tactile Threshold after treatment at 30 min | The tactile threshold will be measured with Von Frey filaments and will be expressed in millinewton | Immediately after treatment at 30 min |
| Muscle Strength after treatment at 30 min | The muscle strength will be measured with a dynamometer and will be expressed in Newton | Immediately after treatment at 30 min |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in Mechanical Pain Threshold | The pressure pain threshold will be measured by a pressure algometer and will be expressed in Newton | baseline at 0 min, immediately after treatment at 30 min |
| Change from baseline in TactileThreshold |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Diego Serrano-Muñoz, MsC | Hospital Nacional de Parapléjicos, Toledo | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Diego Serrano-Muñoz | Toledo | 45004 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32075666 | Derived | Serrano-Munoz D, Avendano-Coy J, Simon-Martinez C, Taylor J, Gomez-Soriano J. 20-kHz alternating current stimulation: effects on motor and somatosensory thresholds. J Neuroeng Rehabil. 2020 Feb 19;17(1):22. doi: 10.1186/s12984-020-00661-x. |
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| Sham Stimulation | Device | Sham transcutaneous electrical stimulation over superficial radial nerve through the electrotherapy device Myomed 932. (Enraf-Nonius, Delft, Netherlands) |
|
The tactile threshold will be measured with Von Frey filaments and will be expressed in millinewton |
| baseline at 0 min, immediately after treatment at 30 min |
| Change from baseline in Muscle strength | The muscle strength will be measured with a dynamometer and will be expressed in Newton | baseline at 0 min, immediately after treatment at 30 min |