Effect of Transcranial Direct-current Stimulation Therapy on Primary Chronic Insomnia Patients

Effect of Transcranial Direct-current Stimulation Therapy on Primary Chronic Insomnia Patients: A Pilot Study.Insomnia Patients

To evaluate the clinical efficacy and safety of neuromodulation by transcranial direct current stimulation (tDCS) in the patients with primary chronic insomnia .

• visit 1

  • to fill in a questionnaire (Clinical Global Impression, CGI; Leeds Sleep Evaluation Questionnaire, LSEQ; Stanford Sleepiness Scale, SSS; Hospital Anxiety and Depression Scale, HADS; 36-Item Short Form Survey, SF-36)
  • EEG

• visit 2-6

  • tDCS stimulation (monday ~ friday)
  • anodal / cathodal / sham
  • to fill in a questionnaire (CGI, LSEQ, SSS, HADS)
  • analysis the results of sleep log and actigraphy

• visit 7 : 1 week after treatment

  • to fill in a questionnaire (CGI, LSEQ, SSS, HADS)
  • analysis the results of sleep log and actigraphy
  • EEG

• visit 8 : 1 month after treatment

  • to fill in a questionnaire (CGI, LSEQ, SSS, HADS, SF-36)
  • analysis the results of sleep log

Inclusion Criteria:

• adult (older than 19 years)
• primary insomnia
• right handed
• agree with participation of this study

Exclusion Criteria:

• diagnosed with epilepsy or history of seizure
• change of antipsychotic drug within 1 month
• under suspicion of sleep apnea or periodic limb movement disorder
• mental retardation (IQ < 70)
• pregnant woman