Microtransplantation in Older Patients With Acute Myeloid Leukemia

International Multi-center Clinical Study on Microtransplantation for Treatment of Newly Diagnosed Elderly Acute Myeloid Leukemia (EAML)

The purpose of this study is to see whether HLA-mismatched donor cells infusion with chemotherapy (microtransplantation，MST) could increase complete remission (CR) and improve survival in older patients with acute myeloid leukemia (AML)，the investigators conducted a prospective, multicenter clinical trial of HLA-mismatched MST to estimate outcomes and toxicities.

Inclusion Criteria:

• de novo acute myeloid leukemia
• age 60-90
• have HLA mismatched donor

Exclusion Criteria:

• have no suitable donor or donor refused
• patient refused to accept donor cells