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This study evaluates the effectiveness of a minimally invasive treatment, consisting of partial polymer-infiltrated-ceramic-network (PICN) restorations, used in case of rehabilitation of advanced and generalized dental wear over a period of 5 years.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| No prep | Other | "No prep" treatment of worn dentition with CAD-CAM composite (PICN) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| "No prep" treatment of worn dentition with CAD-CAM composite | Device | Realization of minimally invasive prostheses in PICN (CAD-CAM composite)for worn dentition. Tooth tissues are preserved: no preparation is performed and ultra-thin restorations are CAD-CAM milled. |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical evaluation of minimally-invasive treatment protocol of worn dentition | Clinical evaluation following FDI criteria | 5 years |
| Quality of life evaluation of minimally-invasive treatment protocol of worn dentition | Quality of life questionnaires | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Toxicology evaluation of PICN restorations mechanical and biological behaviour | Toxicology ex vivo evaluation | 5 years |
| Wear evaluation of PICN restorations mechanical and biological behaviour |
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Inclusion Criteria:
Exclusion Criteria:
More than one missing tooth on each mandible
Patients with crown(s), bridge(s) or implant(s)
Patients with non-stabilized parodontite
Smoker
Patients suffering from :
Conditions or circumstances, in the opinion of the investigator, which would prevent completion of study participation or interfere with analysis of study results, such as history of non-compliance, or unreliability
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Amélie K Mainjot | Contact | a.mainjot@chu.ulg.ac.be | ||
| Julie Oudkerk | Contact | oudkerk.julie@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Amélie Mainjot | University Hospital Center (CHU) of Liège | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Dentistry University of Liege | Recruiting | Liège | 4000 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38762399 | Derived | Oudkerk J, Herman R, Eldafrawy M, Wulfman C, Ernst M, Vanheusden A, Mainjot A. Intraoral wear of PICN CAD-CAM composite restorations used in severe tooth wear treatment: 5-year results of a prospective clinical study using 3D profilometry. Dent Mater. 2024 Jul;40(7):1056-1063. doi: 10.1016/j.dental.2024.05.015. Epub 2024 May 18. |
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| ID | Term |
|---|---|
| D057085 | Tooth Wear |
| ID | Term |
|---|---|
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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Wear ex vivo evaluation
| 5 years |