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It has previously been found that there is no correlation between degree of hydronephrosis and presence of reflux; however this is oftentimes the criteria physicians use to obtain a VCUG.
Investigators conducted a previous retrospective study to evaluate other possible findings on ultrasound that may better predict reflux. Investigators found that if a postnatal ultrasound showed any of the three findings of hydroureter, duplication or dysmorphic kidney, then the odds ratio of detecting reflux was 8.07 (95%CI 3.86, 16.87). The purpose of this study is to perform a randomized prospective study to validate this retrospective study. Investigators hypothesis is that patients with hydronephrosis alone will be more likely to have negative VCUG studies; hence obtaining a VCUG for this indication may not be warranted.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control Group | Other | The control patients will be the patients with antenatal hydronephrosis who get a routine VCUG to evaluate for vesicoureteral reflux, as part of routine care. |
|
| Observation Group | No Intervention | Receives no intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Voiding cystourethrogram | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Development of UTIs | Through study completion, an average of 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| The rate of reflux detected on VCUGs | Through study completion, an average of 4 years | |
| Rate of resolution of hydronephrosis | Through study completion, an average of 4 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Virginia Health System, Pediatric Urology, Battle Bldg | Charlottesville | Virginia | 22908 | United States |
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