Observing Changes in Ventilation Pattern During Procedural Sedation

Observing Changes in Ventilation Pattern During Procedural Sedation

The ventilation (respiratory rate, tidal volume and end-tidal CO2) was monitored for patients receiving procedural sedation during endoscopy procedures in order to observe what changes commonly occur.

The literature does not currently describe which ventilation changes a clinician should watch for to keep a patient safe during procedural sedation provided by fentanyl and propofol. This observational study aimed to record the breath-by-breath respiratory rate, tidal volume and end-tidal CO2 for each patient during procedural sedation for each endoscopy procedure. Data analysis offline will aim to identify any patterns in ventilation which may precede apnea or blood oxygen desaturation. The patterns in ventilation preceding apnea or blood oxygen saturation will be compared and contrasted with the patterns of ventilation during normal ventilation periods.

Inclusion Criteria:

• (i) ASA I, II, or III
• (ii) patients older than eighteen
• (iii) English speaking
• (iv) undergoing a colonoscopy procedure and receiving procedural sedation

Exclusion Criteria:

• (i) inability/refusal of subject to provide informed consent
• (ii) standard colonoscopy exclusion criteria used at the GI lab at the University of Utah
• (iii) patients with severe medical conditions that in the view of the acting physician prohibits participation in the study