Fractionated Microneedle Radiofrequency for Treatment of Primary Axillary Hyperhidrosis

Twenty patients with PAH had 1 session of Fractionated microneedle radiofrequency treatment. Clinical improvement was evaluated using a Hyperhidrosis Disease Severity Scale (HDSS) and photographs were taken using the starch-iodine test at every visit and 4 weeks, 8 weeks, and 24 weeks after the treatment. Skin biopsies were obtained from 3 of the enrolled patients before and after treatment. The satisfaction and adverse reactions of the research participants were recorded at every follow-up visit.

Hyperhidrosis Disease Severity Scale (HDSS)Score = 1 My sweating is never noticeable and never interferes with my daily activitiesScore = 2 My sweating is tolerable but sometimes interferes with my daily activitiesScore = 3 My sweating is barely tolerable and frequently interferes with my daily activitiesScore = 4 My sweating is intolerable and always interferes with my daily activities

Inclusion Criteria: Meet the following conditions

• Diagnosed according to having a score of 3 or 4 on a Hyperhidrosis Disease
• Severity Scale (HDSS);
• Patients aged 18 to 40 years (to the date of screening);
• Not treatment in Axillary area before;
• Understanding the whole process of the study, voluntary participation and signed the informed consent;
• Patient compliance is good, can guarantee in course of observation.

Exclusion Criteria:One of the following is not included in this study:

• Pregnant women, ready to pregnant or lactating women;
• Have a serious heart, lung, kidney and other vital organs and endocrine system lesions and the history
• Need insulin control of diabetes; High blood pressure did not get good controller ;
• Patients with white blood cells <4.0 × 109 / L, or a definite anemia (hemoglobin less than 100g / L), or platelets <100 × 109 / L, or other blood disease;
• Patients with chronic diarrhea, or peptic ulcer nearly 1 year;
• Patients suffering from malignant tumor;
• Patients suffering from acute and chronic infectious diseases;
• Mental disorders, history of alcohol abuse, drug or other substance abuse;
• Other cases which researchers believe that can not enroll.