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| Name | Class |
|---|---|
| Regional One Health | OTHER |
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It is well established that obese women are at an increased risk of stillbirth compared to non obese women. This has led many physicians to begin antenatal testing in obese women in the third trimester through either nonstress tests or biophysical profiles. However, there is little evidence that antenatal testing improves fetal outcomes in obese women. The aim of this study is to determine if antenatal testing improves outcomes in obese women and to determine the optimal mode of testing (either nonstress tests or biophysical profiles).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nonstress test | Experimental | Subjects will undergo weekly nonstress tests beginning at 32 weeks until delivery in addition to monitoring fetal kick counts. A nonstress test is a test in which an external fetal monitor is placed on the mother to defect the fetal heart rate for 20 to 40 minutes. A test is considered reactive if there are more than 2 accelerations in fetal heart rate defined as an increase of at least 15 beats per minute lasting at least 15 seconds in a 20 minute period. |
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| Biophysical profile | Experimental | Subjects will undergo weekly biophysical profile testing beginning at 32 weeks until delivery in addition to monitoring fetal kick counts. A Biophysical profile is a test using real time ultrasonography to determine the presence of absence of certain components of fetal well being. There components include: an episode of fetal breathing lasting at least 30 seconds, 3 or more discrete body movements, 1 or more episodes of extension of a fetal extremity with return to flexion, and determination of amniotic fluid volume to detect a maximum vertical pocket of >2cm. The duration of this test is no more than 30 minutes. |
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| Kick counts only | No Intervention | Subjects will monitor fetal kick counts only. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| External fetal monitor for Nonstress test | Device |
| ||
| Ultrasonography for Biophysical profile |
| Measure | Description | Time Frame |
|---|---|---|
| Stillbirth | demise of infant prior to delivery as verified by ultrasonography | until delivery, up to 41 weeks |
| Mode of delivery | whether the subject undergoes a vaginal delivery, cesarean delivery, or operative delivery will be recorded | at delivery, up to 41 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Neonatal intensive care unit admission admission | at delivery, up to 41 weeks | |
| Apgar score of less than 7 at 5 minutes | at delivery, up to 41 weeks |
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Inclusion Criteria:
less then 32 weeks gestation BMI > 30kg/m2 English speaking
Exclusion Criteria:
age < 18 age >45 medical comorbidity which requires antenatal testing other than obesity unwilling to consent Non-English speaking not pregnant Gestational age >32 weeks
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Laura Grese, MD | Contact | 4235712990 | lgrese@uthsc.edu | |
| Luis Gomez, MD | Contact | lgomez2@uthsc.edu |
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| ID | Term |
|---|---|
| D000079262 | Pregnancy in Obesity |
| ID | Term |
|---|---|
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D009765 | Obesity |
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| ID | Term |
|---|---|
| D015148 | Cardiotocography |
| D014463 | Ultrasonography |
| ID | Term |
|---|---|
| D006334 | Heart Function Tests |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| Device |
|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D005323 | Fetal Monitoring |
| D003944 | Diagnostic Techniques, Obstetrical and Gynecological |
| D008991 | Monitoring, Physiologic |
| D003952 | Diagnostic Imaging |