New Covered Stent (Willis) for the Endovascular Reconstruction of Intracranial Vessel Wall Defects Registry

New Covered Stent (Willis) for the Endovascular Reconstruction of Intracranial Vessel Wall Defects Registry

The purpose of this study is to evaluate the effectiveness, long-term safety and explore the safety and efficacy factors WILLIS™ intracranial stent graft system in clinical applications.

Intracranial aneurysm is a cerebrovascular disorder in which weakness in the wall of a cerebral artery or vein causes a localized dilation or ballooning of the blood vessel.WILLIS® intracranial stent graft system is indicated for the treatment of intracranial aneurysms.

This study is a multi-center, prospective registration study.

Recruiting 100 specific patients to undergo a treatment with the WILLIS intracranial stent graft system, while giving the anti-platelet aggregation drugs and other medical therapy.

Patients enrolled will undergo a one-year follow-up.

Inclusion Criteria:

• Age over 18;
• Arterial wall defects conformed by imaging examination due to internal carotid artery, vertebral artery aneurysms or various causes;
• Target lesion vessel reference diameter 3.5-4.5mm;
• Investigators believe that the patient is suitable for the interventional therapy of WILLIS intracranial covered stent;
• Participate in the study voluntarily, accept follow up study and signed Informed Consent Form.

Exclusion Criteria:

• Existence of branch artery (eg anterior choroidal artery, posterior communicating artery, posterior inferior cerebellar artery, etc.) of target lesion which may cause severe neurological dysfunction after occlusion;
• No suitable vessel entrance, or diseased artery extremely tortuous;
• Coagulation disorders or serious heart, liver, kidney dysfunction or systemic infection, which not suitable for interventional treatment;
• Life expectancy <1 year;
• Contraindications to heparin, aspirin, clopidogrel, anesthesia, X-ray or contrast agents;
• Mental disorder