This study is designed to assess a safe dosage of the drug CXL-1427 (BMS-986231) in healthy volunteers.

Inclusion Criteria:

• No evidence of any acute or chronic health disorder
• Not have taken any prescription medication within 15 days of study entry
• Not have taken any over-the-counter medication or herbal/vitamin supplement within 3 days of study entry
• Not have not have any dietary restrictions
• Have a body mass index (BMI) of ≥18 to ≤34
• Weigh at least 50kg (110 pounds)

Exclusion Criteria:

• Be a current or recent (within 6 months of the Screening Visit) smoker or user of any nicotine-containing product
• Have a history of symptomatic hypotension, orthostatic hypotension or syncope
• Have a history of headaches or other symptoms attributable to caffeine withdrawal
• Have a history of any bleeding diathesis
• Have a positive serology screen for HIV antibody, hepatitis B surface antigen or hepatitis C antibody at screening

Other protocol defined inclusion/exclusion criteria could apply