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A cluster randomised pragmatic trial will be conducted within an emerging clinical information network composed of 12 Kenyan county hospitals. Hospitals will be randomised to an enhanced feedback intervention delivered over a nine-month period and compared to standard feedback. The trial to be implemented during a phase of implementing change in guideline recommendations for pneumonia will assess the impact of enhanced feedback on hospital uptake of the revised pneumonia treatment recommendations.
The international guidelines for the classification and treatment of childhood pneumonia were revised recently and in Kenya the national guidelines changed in February 2016. We designed an enhanced feedback intervention aimed at improving uptake of the revised pneumonia treatment policy within a clinical network of 12 Kenyan county referral hospitals.
Hospitals were randomized to receive either enhanced feedback (n = 6 hospitals) or standard feedback (n = 6 hospitals) delivered over a six-month period following nationwide pneumonia treatment policy change. The primary outcome is the proportion of all pneumonia admissions (fulfilling criteria for treatment with oral amoxicillin) who are correctly classified and treated using new guideline recommendations. The proportion of treatment change from oral amoxicillin to alternative antibiotics for pneumonia (considered a proxy measure of treatment failure) will be reported as a secondary outcome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Enhanced feedback | Experimental |
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| Standard feedback | Active Comparator |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Enhanced feedback | Behavioral | Hospital level feedback delivered every month through paediatrician on the level of adherence to revised pneumonia treatment recommendations. |
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| Measure | Description | Time Frame |
|---|---|---|
| Pneumonia classification and treatment | The proportion of all pneumonia admissions (fulfilling criteria for treatment with oral amoxicillin) who are correctly classified and treated using new guideline recommendations | 9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Antibiotic change | The proportion of treatment change from oral amoxicillin to alternative antibiotics for pneumonia (considered a proxy measure of treatment failure) | 9 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mike English, MD | KEMRI-Wellcome Trust Research Priogramme | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kerugoya County Hospital | Kerugoya | Kerugoya | Kenya | |||
| Busia County Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30832678 | Derived | Ayieko P, Irimu G, Ogero M, Mwaniki P, Malla L, Julius T, Chepkirui M, Mbevi G, Oliwa J, Agweyu A, Akech S, Were F, English M; Clinical Information Network Authors. Effect of enhancing audit and feedback on uptake of childhood pneumonia treatment policy in hospitals that are part of a clinical network: a cluster randomized trial. Implement Sci. 2019 Mar 4;14(1):20. doi: 10.1186/s13012-019-0868-4. | |
| 28877729 |
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| ID | Term |
|---|---|
| D011014 | Pneumonia |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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| Standard feedback | Behavioral | Hospital level feedback delivered every two months through paediatrician on the performance of multiple paediatric care indicators for managing severely ill children. |
|
| Busia |
| Kenya |
| Embu County Hospital | Embu | Kenya |
| Kakamega County Referral Hospital | Kakamega | Kenya |
| Vihiga County Hospital | Kakamega | Kenya |
| Karatina County Hospital | Karatina | Kenya |
| Kiambu County Hospital | Kiambu | Kenya |
| Kisumu County Hospital | Kisumu | Kenya |
| Kitale County Hospital | Kitale | Kenya |
| Machakos County Hospital | Machakos | Kenya |
| Mama Lucy Kibaki Hospital | Nairobi | Kenya |
| Nyeri County Hospital | Nyeri | Kenya |
| Derived |
| Ayieko P, Irimu G, English M. Effect of enhanced feedback to hospitals that are part of an emerging clinical information network on uptake of revised childhood pneumonia treatment policy: study protocol for a cluster randomized trial. Trials. 2017 Sep 7;18(1):416. doi: 10.1186/s13063-017-2152-8. |