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| Name | Class |
|---|---|
| Massachusetts General Hospital | OTHER |
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This study investigates the clinical and neural effects of stress management skill building programs for young adults with childhood adversity. The investigators will recruit a total of 60 young adults (21-35 years old) who will be randomized into two different stress management skill building programs, both of which are 8 weeks long. MRI and psychological assessments will be acquired from all subjects before and after the intervention programs in order to investigate changes in clinical symptoms (such as depression, anxiety and stress) and hippocampus structure and function as well as other neural changes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Stress Management Skill Building Program A | Experimental | An eight week skill building group in which subjects meet with the teacher and other students in the group once a week, and complete homework and practice log during the week. |
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| Stress Management Skill Building Program B | Active Comparator | An eight week skill building group in which subjects meet with the teacher and other students in the group once a week, and complete homework and practice log during the week. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Stress Management Skill Building Program A | Behavioral | Subject will meet with the instructor and other students in the group once a week and complete homework and track amount of practice during the week. |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in hippocampal subfield gray matter density measured with high resolution structural MRI at 3T | before and after the 8-week intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in stress level measured by the Perceived Stress Scale (PSS) | before and after the 8-week intervention | |
| Changes in severity of depression symptom measured by Beck Depression Inventory (BDI) | before and after the 8-week intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Diane Joss, PhD | Mclean Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| McLean Hospital | Belmont | Massachusetts | 02478 | United States |
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| ID | Term |
|---|---|
| D003863 | Depression |
| D001008 | Anxiety Disorders |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D001523 | Mental Disorders |
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| Stress Management Skill Building Program B | Behavioral | Subject will meet with the instructor and other students in the group once a week and complete homework and track amount of practice during the week. |
|
| Changes in severity of anxiety symptom measured by State-Trait Anxiety Inventory (STAI) | before and after the 8-week intervention |