Safety and Exploratory Efficacy Study of UCMSCs in Patients With Fracture and Bone Nonunion

The purpose of the present study is to evaluate the safety and exploratory efficacy of the umbilical cord mesenchymal stem cells for patients with fracture and bone nonunion.

Inclusion Criteria:

• Every patient with non union in the site of bone fracture and nonunion.
• Age more than 18 and less than 60 years old.
• Nonunion or delayed union.

Exclusion Criteria:

• Diagnosis of cancer.
• Pregnancy or breastfeeding.
• Patient positive by serology or PCR for HIV, hepatitis B or C infection the patient with Accompanied fracture such as hip fracture that could not weight bearing.
• Any medical or psychiatric condition that in the researcher´s opinion could affect the patient´s ability to complete the trial or hamper the participation in the trial.
• Patients do not sign the consent forms