Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study evaluated whether laser acupuncture at the time of embryo transfer (following in vitro fertilization) improves implantation rates. Patients were randomized to one of 4 groups at the time of embryo transfer: 1) laser acupuncture, 2) needle acupuncture, 3) sham laser acupuncture, 4) no treatment.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Needle Acupuncture | Experimental | Sterile, disposable needles were inserted into specific acupoints until Deqi sensation was elicited. The needles were retained for 25 minutes before and after embryo transfer. |
|
| Laser Acupuncture | Experimental | Each point was stimulated with a laser (Luminex Laser Therapy System: Medical Laser Systems, Branford, CT) set at 5 joules/cm2 (J/cm2) in continuous mode for 0.10 seconds. Based on various studies, a minimum of 4 J/cm2 produces an improved circulatory effect. |
|
| Sham Laser Acupuncture | Sham Comparator | However, support staff uninvolved in the design of the trial or analysis of the data disarmed the machine, such that no laser irradiation was emitted. This system created an illusion for both the patient and the acupuncturist, and allowed for a truly double blinded control group. |
|
| No Treatment | No Intervention | This control group was not exposed to any additional physical contact or acupuncture related protocol. They were only exposed to dim light and calming music before and after embryo transfer, mimicking the natural waiting room and procedure room setting for all patients undergoing embryo transfer. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Needle Acupuncture | Procedure | See above |
| |
| Laser Acupuncture |
| Measure | Description | Time Frame |
|---|---|---|
| Implantation rate | Number of gestational sacs seen on ultrasound per embryo transferred | Approximately 2 weeks after embryo transfer |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical pregnancy rate | Number of pregnancies per embryo transfer procedure | Approximately 3 weeks after embryo transfer |
| Live birth rate | Number of deliveries of at least on live newborn per embryo transfer procedure |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Reproductive Medicine Associates of Connecticut | Norwalk | Connecticut | 06850 | United States | ||
| Reproductive Medicines Associates of New Jersey |
Not provided
Not provided
Not provided
Not provided
Not provided
| Procedure |
See above |
|
| Sham Laser Acupuncture | Procedure | See above |
|
| 40 weeks after intervention |
| Morristown |
| New Jersey |
| 07960 |
| United States |