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The investigators performed randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Cordyceps sinensis mycelium culture extract (Paecilomyces hepiali, CBG-CS-2) on promotion of immunity. The investigators measured promotion of immunity parameters , including Cytotoxicity, Cytokine (IL-1β, IL-2, IL-4, IL-10, IL-12, IFN-γ, TNF-α).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cordyceps sinensis mycelium culture extract | Experimental | Cordyceps sinensis mycelium culture extract 1.68 g |
|
| Placebo | Placebo Comparator | Placebo |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cordyceps sinensis mycelium culture extract 1.68 g | Dietary Supplement | Cordyceps sinensis mycelium culture extract 1.68 g |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in serum natural killer cell activity | Baseline, 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Cytokine(IL-1β, IL-2, IL-4, IL-10, IL-12, IFN-γ, TNF-α) | Baseline, 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Trial Center for Functional Foods; Chonbuk National University Hospital | Jeonju | Jeollabuk-do | 560-822 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30925876 | Derived | Jung SJ, Jung ES, Choi EK, Sin HS, Ha KC, Chae SW. Immunomodulatory effects of a mycelium extract of Cordyceps (Paecilomyces hepiali; CBG-CS-2): a randomized and double-blind clinical trial. BMC Complement Altern Med. 2019 Mar 29;19(1):77. doi: 10.1186/s12906-019-2483-y. |
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| Placebo | Dietary Supplement |
|