Assessment of Coronary Artery Lesion Using Optical Coherence Tomography Versus IntraVascular Ultrasound for BiorEsorbable Vascular Scaffold Implantation

Assessment of Coronary Artery Lesion Using Optical Coherence Tomography Versus IntraVascular Ultrasound for BiorEsorbable Vascular Scaffold Implantation

The primary objective is to determine whether IVUS- (vs. OCT-) guided BVS implantation is non-inferior to achieve a large in-scaffold minimal lumen area (primary endpoint) measured by OCT at 1-year follow-up.

Inclusion Criteria:

• Age 20 years or older
• Patients who have at least one epicardial coronary artery lesion with an evidence of inducible ischemia
• Willing and able to provide informed written consent
• Eligible for PCI

Exclusion Criteria:

• Patients presenting with STEMI within 2 weeks
• Bypass graft lesion
• Lesion with left main disease
• Expected length of scaffold > 40 mm
• Bifurcation lesion requiring side branch stenting
• Small vessels < 2.75 mm
• Stented lesion
• Suspected coronary spasm even after sufficient nitrate injected
• Cases in which the IVUS or OCT imaging catheter failed to cross the lesion
• Poor quality IVUS or OCT images
• Contraindication to dual anti-platelet therapy
• Chronic total occlusion
• Angiographically large-sized vessel (>3.5mm of reference lumen diameter)
• Life expectancy shorter than 2 years
• Pregnancy