Comparison of 22-gauge and 19-gauge Aspiration Needle During EBUS-TBNA

Comparison of the Diagnostic Yield Between Various Endobronchial Ultrasound-guided-transbronchial Needles (EBUS-TBN) to Evaluate Suspect Mediastinal and Hilar Lymph Nodes

Investigators intend to compare the 19-gauge needle and the 22-gauge-needle during EBUS-TBNA concerning the diagnostic yield, the quality and quantity of each biopsy needle without raising the rate of complications.

Investigators intend to compare the 19-gauge needle and the 22-gauge-needle during EBUS-TBNA performed in rigid bronchoscopy for patients with probable lung cancer diagnosis and enlarged mediastinal lymph nodes.

Inclusion Criteria:

• Male or female patients aged over 18
• Patients signed written informed consent
• Mediastinal or hilar enlarged lymph nodes (>10mm) in short axis radiological or clinical findings likely for lung cancer

Exclusion Criteria:

• Severe impairment of any organs, with do not enable anaesthesia
• Quick <80%, INR >1,5, thrombocytes <50/nl or PTT>120sec
• Other clinically relevant medical or psychological diseases, which affect the patients judgement or ability to participate in this study.
• Insufficient language ability (spoken and written German)