Impact of Oral Phosphorus Supplements on the 6-month Change in FGF23 Levels in Anorexic Adolescents Suffering From Undernutrition.

Impact of Oral Phosphorus Supplements on the 6-month Change in FGF23 Levels in Anorexic Adolescents Suffering From Undernutrition.

Fibroblast growth factor 23 (FGF23) is a recently discovered phosphaturic hormone produced by osteocytes. It is involved in phosphate-calcium metabolism (via its phosphaturic action and inhibition of 1,25-OH vitamin D).

There are no published studies on the role of FGF23 in undernourished anorexic adolescents taking oral phosphorus supplements.

Inclusion Criteria:

• Adolescents aged from 11 to 17
• Follow-up or hospitalisation for anorexia
• Overt undernutrition (clinical signs of undernutrition, body mass index and the Waterlow index)
• Social security coverage

Exclusion Criteria:

• Known pre-existing renal disorders
• Known constitutional disorders of phosphate-calcium metabolism
• Adult patients, legal guardianship, incarceration