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A prospective bariatric database was carried out in the Department of Digestive and Endocrine Surgery at the University Hospital of Strasbourg, France, starting in January 1996. All potential candidates for obesity surgery were prospectively registered in the database. Patients were informed by the bariatric surgeon of the prospective database, and of the possibility of utilizing personal data for research purpose after anonymization.
A case-control study was performed, to compare the quality of life (QoL) of patients treated for internal hernia (IH group) with the QoL of patients with an uncomplicated course after Roux en Y gastric bypass (Uncomplicated RYGB group).
A prospective bariatric database was carried out in the Department of Digestive and Endocrine Surgery at the University Hospital of Strasbourg, France, starting in January 1996. All potential candidates for obesity surgery were prospectively registered in the database. Patients were informed by the bariatric surgeon of the prospective database, and of the possibility of utilizing personal data for research purpose after anonymization. Patients were evaluated by a multidisciplinary team. The standard preoperative assessment included nutritional counseling, psychological evaluation, abdominal ultrasound, upper gastrointestinal endoscopy, and blood tests. Type and date of surgery, biological and clinical follow-up data and morbidity data were recorded prospectively in the database.
A case-control study was performed, to compare the quality of life (QoL) of patients treated for internal hernia (IH group) with the QoL of patients with an uncomplicated course after Roux en Y gastric bypass (Uncomplicated RYGB group). Patients who had IH were paired with patients of the same age and sex and at the same postoperative interval. Paired patients were contacted by phone to obtain the QoL questionnaires, abdominal pain evaluation, and weight loss data.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Roux en Y gastric bypass | Procedure | Laparoscopic RYGB is performed as following: a gastric pouch of approximately 30mL was obtained using successive firings of the Endo GIATM linear stapler, followed by the creation of an antecolic alimentary limb of 150cm and of a biliopancreatic limb of 75cm. A gastrojejunal anastomosis was fashioned with the PCEEAâ„¢ 28 circular stapler until 2012, and using the Endo GIAâ„¢ linear stapler afterwards. The mesenteric defect and Petersen's defect were closed using a non-absorbable running suture. | ||
| Sleeve gastrectomy | Procedure | Laparoscopic SG is performed as following: after greater curvature mobilization, the gastric tube was calibrated over a 36F bougie and transection started approximately 5-6 cm from the pylorus toward the left diaphragmatic crus, using successive firings of 3.5- or 4.8-mm-high staples, depending on gastric thickness. | ||
| Gastric banding | Procedure | Laparoscopic gastric banding is performed as following: a perigastric tunel is performed by blunt dissection and the banding is calibrated over the stomach. | ||
| Intragastric balloon | Procedure | Flexible endoscopy is used to place intragastric balloon for a maximum interval of six months. |
| Measure | Description | Time Frame |
|---|---|---|
| Excess weight loss | 1 - 3 - 5 - 10 - 15 and 30 years |
| Measure | Description | Time Frame |
|---|---|---|
| BMI | 1 - 3 - 5 - 10 - 15 and 30 years | |
| Albumin | Albumin | 1 - 3 - 5 - 10 - 15 and 30 years |
| Pre-albumin |
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Inclusion Criteria:
Exclusion Criteria:
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Patient >18 years old BMI >35 kg/m²
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Didier Mutter, MD, PhD | Contact | +33 (0)3 90 11 90 41 | didier.mutter@chru-strasbourg.fr |
| Name | Affiliation | Role |
|---|---|---|
| Didier Mutter, MD, PhD | Department of Digestive and Endocrine Surgery, University Hospital of Strasbourg | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Chirurgie Digestive et Endocrinienne | Recruiting | Strasbourg | 67000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15946441 | Result | Lunca S, Vix M, Rikkers A, Rubino F, Marescaux J. Late gastric prolapse with pouch necrosis after laparoscopic adjustable gastric banding. Obes Surg. 2005 Apr;15(4):571-5. doi: 10.1381/0960892053723420. | |
| 21444079 | Result | Donatelli G, Costantino F, Dhumane P, Vix M, Perretta S, D' Agostino J, Dallemagne B, Marescaux J. Endoscopic intragastric balloon: a bridge toward definitive bariatric surgical management of a morbidly obese patient with situs ambiguous and midgut malrotation (with videos). Gastrointest Endosc. 2012 Jan;75(1):217-8. doi: 10.1016/j.gie.2011.01.022. Epub 2011 Mar 27. No abstract available. |
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| ID | Term |
|---|---|
| D009767 | Obesity, Morbid |
| ID | Term |
|---|---|
| D009765 | Obesity |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
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| ID | Term |
|---|---|
| D015390 | Gastric Bypass |
| ID | Term |
|---|---|
| D050110 | Bariatric Surgery |
| D049088 | Bariatrics |
| D000073319 | Obesity Management |
| D013812 | Therapeutics |
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Pre-albumin |
| 1 - 3 - 5 - 10 - 15 and 30 years |
| Vitamin A | Vitamin A | 1 - 3 - 5 - 10 - 15 and 30 years |
| Vitamin D | Vitamin D | 1 - 3 - 5 - 10 - 15 and 30 years |
| Vitamin B6 | Vitamin B6 | 1 - 3 - 5 - 10 - 15 and 30 years |
| Vitamin B9 | Vitamin B9 | 1 - 3 - 5 - 10 - 15 and 30 years |
| Vitamin B12 | Vitamin B12 | 1 - 3 - 5 - 10 - 15 and 30 years |
| Plasma ferritin | Plasma ferritin | 1 - 3 - 5 - 10 - 15 and 30 years |
| Fasting plasma glucose | Fasting plasma glucose | 1 - 3 - 5 - 10 - 15 and 30 years |
| Serum insulin | Serum insulin | 1 - 3 - 5 - 10 - 15 and 30 years |
| HbA1c | HbA1c | 1 - 3 - 5 - 10 - 15 and 30 years |
| Triglycerides | Triglycerides | 1 - 3 - 5 - 10 - 15 and 30 years |
| Cholesterol | Cholesterol (total, HDL, LDL) | 1 - 3 - 5 - 10 - 15 and 30 years |
| Quality of life assessed by Moorehead-Ardelt Quality of life II questionnaire | Moorehead-Ardelt Quality of life II questionnaire | 1 - 3 - 5 - 10 - 15 and 30 years |
| Quality of life assessed by Gastro-intestinal Quality of Life Index | Gastro-intestinal Quality of Life Index | 1 - 3 - 5 - 10 - 15 and 30 years |
| Postoperative morbidity | Postoperative morbidity | 1 - 3 - 5 - 10 - 15 and 30 years |
| 23207829 | Result | Vix M, Diana M, Liu KH, D'Urso A, Mutter D, Wu HS, Marescaux J. Evolution of glycolipid profile after sleeve gastrectomy vs. Roux-en-Y gastric bypass: results of a prospective randomized clinical trial. Obes Surg. 2013 May;23(5):613-21. doi: 10.1007/s11695-012-0827-5. |
| 24196556 | Result | Vix M, Liu KH, Diana M, D'Urso A, Mutter D, Marescaux J. Impact of Roux-en-Y gastric bypass versus sleeve gastrectomy on vitamin D metabolism: short-term results from a prospective randomized clinical trial. Surg Endosc. 2014 Mar;28(3):821-6. doi: 10.1007/s00464-013-3276-x. Epub 2013 Nov 7. |
| D009750 |
| Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D005763 |
| Gastroenterostomy |
| D000714 | Anastomosis, Surgical |
| D013514 | Surgical Procedures, Operative |
| D013505 | Digestive System Surgical Procedures |