Effects of Preoperative Oral Carbohydrates Loading in Patients at High Risk of Postoperative Nausea and Vomiting Undergoing Spinal Surgery

Many patients receiving opioid based analgesia after spinal surgery experience postoperative nausea and vomiting (PONV) despite prophylaxis and treatment with antiemetic agents. Dehydration caused by fasting prior to surgery is associated with the development of PONV. The aim of this study is to investigate the effect of oral carbohydrates loading prior to surgery in patients at high risk of PONV undergoing spinal surgery.

Inclusion Criteria:

• female patient between 20 and 65 of age with ASA physical status Ⅰ-Ⅱ
• patient scheduled for elective spine surgery
• no smoking history

Exclusion Criteria:

• hepatorenal disease
• BMI > 35 kg/m2
• gastrointestinal disease
• vomiting within 24h
• administration of antiemetics or opioids within 24 h prior to surgery
• pregnant
• problem with communication