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| Name | Class |
|---|---|
| Health Resources and Services Administration (HRSA) | FED |
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The objectives of this research study are to screen 750 pregnant women at risk of trauma-related stress symptoms, and adapt and test an evidence-based intervention for pregnant women with PTSD and sub-threshold PTSD symptoms served by two public payer community health centers.
Studies of Posttraumatic Stress Disorder (PTSD) in pregnant women in public payer settings have shown rates 5 or more times that of other populations, and rates as high as 33% of lifetime PTSD sub-threshold symptoms. PTSD during pregnancy has been linked to poor prenatal care and high risk behaviors such as drug and alcohol use and smoking. Further, PTSD may pose a barrier to care as obstetric procedures and pregnancy may trigger PTSD symptoms and avoidance of care. PTSD is also associated with pregnancy and birth complications and negative postpartum outcomes including excessive weight gain, preterm birth, low birth weight, risk for parenting problems, and increased barriers to breastfeeding. However, screening, identification, and support for PTSD is lacking. This study will screen 750 pregnant women at risk of trauma-related stress symptoms, and adapt and test an evidence-based intervention for pregnant women with PTSD and sub-threshold PTSD symptoms served by two public payer community health centers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental | Experimental | Intervention mothers receive adapted Seeking Safety intervention delivered by prenatal care advocate over 8 sessions |
|
| No intervention | No Intervention | Treatment as usual mothers receive usual services of a prenatal care advocate |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Adapted Seeking Safety Intervention | Behavioral | Intervention participants received Seeking Safety psychosocial education Intervention adapted for prenatal care setting. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in posttraumatic stress disorder symptoms | The primary endpoint is one month postpartum | |
| Preterm labor | the primary endpoint is one month postpartum | |
| Birthweight | the primary endpoint is one month postpartum |
| Measure | Description | Time Frame |
|---|---|---|
| Number of visits for prenatal care | the primary end point is one month postpartum | |
| Change in depression symptoms | the primary endpoint is one month postpartum | |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37146219 | Derived | Jones KA, Freijah I, Brennan SE, McKenzie JE, Bright TM, Fiolet R, Kamitsis I, Reid C, Davis E, Andrews S, Muzik M, Segal L, Herrman H, Chamberlain C. Interventions from pregnancy to two years after birth for parents experiencing complex post-traumatic stress disorder and/or with childhood experience of maltreatment. Cochrane Database Syst Rev. 2023 May 4;5(5):CD014874. doi: 10.1002/14651858.CD014874.pub2. | |
| 29116416 |
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| ID | Term |
|---|---|
| D013313 | Stress Disorders, Post-Traumatic |
| ID | Term |
|---|---|
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |
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| change in coping strategies inventory |
| the primary endpoint is one month postpartum |
| Derived |
| Weinreb L, Wenz-Gross M, Upshur C. Postpartum outcomes of a pilot prenatal care-based psychosocial intervention for PTSD during pregnancy. Arch Womens Ment Health. 2018 Jun;21(3):299-312. doi: 10.1007/s00737-017-0794-x. Epub 2017 Nov 7. |