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Through comparative observation of robot vagus nerve preserving distal gastric cancer radical surgery and conventional robot distal gastric cancer radical surgery (not reserved vagus nerve) operative and postoperative indicators, and evaluating the feasibility and safety of vagus nerve preserving distal gastric cancer radical surgery in advanced gastric cancer. Which can provide the evidences for the clinical development of the preserving function gastric cancer surgery.
Compare the robot vagus nerve preserving distal gastric cancer radical surgery and conventional robot distal gastric cancer radical surgery (not reserved vagus nerve). Observe the operative and postoperative indicators, and evaluate the feasibility and safety of vagus nerve preserving distal gastric cancer radical surgery in advanced gastric cancer. Which can provide the evidences for the clinical development of the preserving function gastric cancer surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| VPRDG for AGC | Experimental | Vagus nerve-preserving Robot-assisted distal subtotal gastrectomy (VPRDG) with D2 lymphadenectomy will be performed for the treatment of patients assigned to this group. |
|
| CRDG FOR AGC | Active Comparator | Conventional Robot-assisted distal subtotal gastrectomy (CRDG) with D2 lymphadenectomy without preserving vagus nerve will be performed for the treatment of patients assigned to this group. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vagus nerve-preserving Robot-assisted Gastrectomy | Procedure |
| ||
| Conventional Robot-assisted Gastrectomy |
| Measure | Description | Time Frame |
|---|---|---|
| Recurrence rate | Recurrence rate in 3 years after operating. | up to 36 months |
| Measure | Description | Time Frame |
|---|---|---|
| 3-years survival rate | Survival rate in 3 years after operating. | up to 36 months |
| The rate of Calculus of gallbladder | The rate of gallbladder calculus in 1 year after operating, which is diagnosed by ultrasound. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yingxue Hao, M.D. | Contact | 086-2368754167 | haoyingxue@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Yingxue Hao, M.D. | Southwest Hospital, Third Military Medical University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Southwest Hospital | Chongqing | Chongqing Municipality | 400038 | China |
Yes, the investigators can share the data with other.
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| ID | Term |
|---|---|
| D013274 | Stomach Neoplasms |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| Procedure |
|
| up to 12 months |
| Number of retrieving lymph nodes | The number of dissecting lymph nodes during operating. | up to 1 week |
| Inflammatory factors | Detecting Interleukin -10 (IL-10), C-reactive protein (CRP) and Tumor Necrosis Factor (TNF-a) in 6 h, 12 h, 24 h, and 72h after operating. | 6 h, 12 h, 24 h, and 72h after operating |
| D004066 |
| Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D013272 | Stomach Diseases |