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The implementation of a medication reconciliation intervention including: medication reconciliation on admission and discharge, bedside medication counselling and take-home medication list, on the development of adverse drug events within 30 days post discharge as primary outcome. Secondary outcome is the evaluation of its impact on health care resource utilization
This is a randomized controlled trial in 587 patients randomized to intervention and usual care. The intervention is medication reconciliation on admission and discharge, bedside medication counselling and take-home medication list. Usual care is ward pharmacy practice. The primary outcomes are preventable and potential adverse drug events at 30 days post discharge. The secondary outcome is health care utilization: length of stay, emergency room visits, unplanned hospital visits, readmissions and travel abroad to seek medical attention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| medication reconciliation intervention | Experimental | medication reconciliation intervention comprises medication reconciliation on admission and discharge, bedside medication counseling and take-home medication list |
|
| usual care | No Intervention | Usual care provided by ward pharmacist, nurses and doctors in the ward |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| medication reconciliation intervention | Other | medication reconciliation intervention comprises medication reconciliation on admission and discharge, bedside medication counseling and take-home medication list |
| Measure | Description | Time Frame |
|---|---|---|
| number of patients with a preventable adverse drug event | 30 days | |
| number of potential adverse drug events | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| number of emergency room visits | 30 days | |
| number of unplanned hospital visits | 30 days | |
| number of hospital readmissions |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Amna Al-Hashar, PhD candidate | Sultan Qaboos University College of Medicine and Health Sciences | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16534045 | Background | Schnipper JL, Kirwin JL, Cotugno MC, Wahlstrom SA, Brown BA, Tarvin E, Kachalia A, Horng M, Roy CL, McKean SC, Bates DW. Role of pharmacist counseling in preventing adverse drug events after hospitalization. Arch Intern Med. 2006 Mar 13;166(5):565-71. doi: 10.1001/archinte.166.5.565. | |
| 22751755 | Background |
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| ID | Term |
|---|---|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
| ID | Term |
|---|---|
| D064419 | Chemically-Induced Disorders |
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| 30 days |
| number of patients who traveled abroad to seek second medical opinion | 30 days |
| Kripalani S, Roumie CL, Dalal AK, Cawthon C, Businger A, Eden SK, Shintani A, Sponsler KC, Harris LJ, Theobald C, Huang RL, Scheurer D, Hunt S, Jacobson TA, Rask KJ, Vaccarino V, Gandhi TK, Bates DW, Williams MV, Schnipper JL; PILL-CVD (Pharmacist Intervention for Low Literacy in Cardiovascular Disease) Study Group. Effect of a pharmacist intervention on clinically important medication errors after hospital discharge: a randomized trial. Ann Intern Med. 2012 Jul 3;157(1):1-10. doi: 10.7326/0003-4819-157-1-201207030-00003. |