Physiopathological and Therapeutic Value of microRNA in t... | NCT02804659

Studies
Physiopathological and Therapeutic Value of microRNA in the Progression of Carotid Artery Plaques: Carotid Protocol and microRNA

NCT02804659

Sponsor

Centre Hospitalier Universitaire, Amiens

Status

Completed

Last Update Posted

Jun 12, 2026Actual

Enrollment

14Actual

Phase

Not provided

Conditions

Carotid Arteries

Interventions

microRNA

Countries

France

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jun 2026

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Mar 26, 2015Actual

Primary Completion Date

Feb 26, 2018Actual

Completion Date

Feb 26, 2018Actual

First Submitted Date

Jun 15, 2016

First Submission Date that Met QC Criteria

Jun 16, 2016

First Posted Date

Jun 17, 2016Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jun 11, 2026

Last Update Posted Date

Jun 12, 2026Actual

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

Retention

Enrollment

14Actual

Arms/Interventions Module

Arm Groups

Not provided

Interventions

Name	Type	Description	Arm Group Labels	Other Names
microRNA	Other	Extraction of the microRNA using the mirVana miRNA isolation kit and quantification using real-time PCRs

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
expression level of the seven miRNAs of interest	expression level of the seven miRNAs of interest in the serum and in carotid artery plaques : miR-100, miR-125a, miR-127, miR-133a, miR-145, miR-221	Day of surgery

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Adults having to undergo carotid thromboendarteriectomy
social security coverage
provision of study information
consent to participation.

Exclusion Criteria:

Previous carotid artery surgery
refusal to participate in the study
or inability to give consent.

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

Not provided

Standard Ages

AdultOlder Adult

Study Population

Adults having to undergo carotid thrombendarteriectomy

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Pierre MAITRIAS, PhD	CHU Amiens	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
CHU Amiens		Amiens		80054	France

Intervention Browse Module

MeSH Terms

ID	Term
D035683	MicroRNAs

Ancestor Terms

ID	Term
D016372	RNA, Antisense
D016375	Antisense Elements (Genetics)
D009706	Nucleic Acids, Nucleotides, and Nucleosides
D012313	RNA

Browse Leaves

Not provided

Browse Branches

Not provided