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This study evaluates corticosteroids in the treatment of obstructive jaundice in autoimmune pancreatitis and/or immunoglobulin G4 (IgG4)-related sclerosing cholangitis in adults. Half of participants will receive corticosteroids alone, while the other half will receive corticosteroids with biliary stent at the beginning.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Steroids group | Active Comparator | The patients will be treated with oral corticosteroids (prednisone 0.6mg/kg/d) alone. |
|
| Stent group | Active Comparator | The patients will be treated with oral corticosteroids and biliary stent. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| corticosteroids | Drug | prednisone 0.6mg/kg/d |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical remission rate of obstructive jaundice | Day 60 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Aiming Yang, M.D. | Contact | +86-10-69151593 | yangaiming@medmail.com.cn |
| Name | Affiliation | Role |
|---|---|---|
| Aiming Yang, M.D. | Peking Union Medical College Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking Union Medical College Hospital | Recruiting | Beijing | Beijing Municipality | 100730 | China |
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| biliary stent |
| Procedure |
placement of biliary stent during endoscopic retrograde cholangiopancreatography (ERCP) |
|
| ID | Term |
|---|---|
| D000081012 | Autoimmune Pancreatitis |
| D041781 | Jaundice, Obstructive |
| ID | Term |
|---|---|
| D050500 | Pancreatitis, Chronic |
| D010195 | Pancreatitis |
| D010182 | Pancreatic Diseases |
| D004066 | Digestive System Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D007565 | Jaundice |
| D006932 | Hyperbilirubinemia |
| D012877 | Skin Manifestations |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D000305 | Adrenal Cortex Hormones |
| ID | Term |
|---|---|
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
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