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Respiratory changes in aortic blood velocity have been described as an indicator of fluid responsiveness when measured in the left ventricular outflow tract by trans esophageal echography. A threshold value of 12% allowed discrimination between responders and nonresponders with a sensitivity of 100% and a specificity of 89%. The suprasternal window is already used to measure cardiac output. The primary endpoint of this study is to determine the predictive value of the respiratory variability in aortic blood velocity measured by suprasternal view (∆VpicSS) as an indicator of fluid responsiveness. The secondary endpoint is to compare maximum velocity and velocity time integral measured by suprasternal and transthoracic view.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fluid challenge with 250 ml of Ringer Lactate | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fluid challenge with 250 ml of Ringer Lactate | Device | Fluid challenge with 250 ml of Ringer Lactate over less than 2 minutes, intra-venous, help by a syringe of 50 ml. Measure of peak velocity before and after the fluid challenge |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of cardiac flow variability | Percentage of cardiac flow variability between the 2 echographic measures. Echographic measures will be realized a first time before fluid challenge by suprasternal view and a second time after the fluid challenge by suprasternal view. | At day 1(before surgery) |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of percentage of cardiac flow variability between transthoracic and suprasternal views | Echographic measures will be realized a first time before fluid challenge by transthoracic and by suprasternal view and a second time after the fluid challenge by transthoracic and by suprasternal view. | At day 1(before surgery) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pauline Devauchelle, MD | Hopital de la Croix-Rousse | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hopital de la Croix-Rousse, Hospices Civils de Lyon | Lyon | 69002 | France |
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