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Patients undergoing vocal cord surgery (phonosurgery) are often prescribed voice rest postoperatively. However, no clinical trials have ever been conducted to ascertain the efficacy of using voice rest and its impact on functional voice outcomes. The purpose of this randomized-clinical trial is to determine if the prescription of voice rest has an impact on voice outcomes following phonosurgery.
The study will seek to determine if a 7-day period of absolute voice rest alters voice-related quality of life following phonosurgery
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | No Intervention | Patients in the control arm will undergo a graduated prescription of voice use immediately following surgery. | |
| Absolute Voice Rest | Experimental | Patients in the experimental arm will undergo 7 days of absolute voice rest following surgery. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Absolute Voice Rest | Behavioral | Patients will be instructed to not use their voice and minimize any voice-use activities such as coughing or throat-clearing for a period of 7 days following surgery. |
| Measure | Description | Time Frame |
|---|---|---|
| Voice Handicap Index (VHI)-10 | 4 weeks post-operative | |
| Voice Handicap Index (VHI)-10 | 12 weeks post-operative |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency perturbation (jitter) | 4 weeks post-operative | |
| Frequency perturbation (jitter) | 12 weeks post-operative | |
| Amplitude perturbation (shimmer) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kevin Fung, MD, FRCSC | Contact | Kevin.Fung@lhsc.on.ca |
| Name | Affiliation | Role |
|---|---|---|
| Kevin Fung, MD, FRCSC | Department of Otolaryngology - Head & Neck Surgery, Western University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| London Health Sciences Centre | Recruiting | London | Ontario | N6A 5W9 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31498467 | Derived | Dhaliwal SS, Doyle PC, Failla S, Hawkins S, Fung K. Role of voice rest following laser resection of vocal fold lesions: A randomized controlled trial. Laryngoscope. 2020 Jul;130(7):1750-1755. doi: 10.1002/lary.28287. Epub 2019 Sep 9. |
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| 4 weeks post-operative |
| Amplitude perturbation (shimmer) | 12 weeks post-operative |
| Fundamental frequency | 4 weeks post-operative |
| Fundamental frequency | 12 weeks post-operative |
| Maximum phonation time | 4 weeks post-operative |
| Maximum phonation time | 12 weeks post-operative |
| Perceptual grading of voice using the Grade, Roughness, Breathiness, Asthenia, Strain, Instability (GRBASI)-scale | 4 weeks post-operative |
| Perceptual grading of voice using the Grade, Roughness, Breathiness, Asthenia, Strain, Instability (GRBASI)-scale | 12 weeks post-operative |